Rubredoksin—NAD(P)+ reduktaza
Rubredoksin—NAD(P)+ reduktaza (EC 1.18.1.4, rubredoksin-nikotinamid adenin dinukleotid (fosfat) reduktaza, rubredoksin-nikotinamid adenin, dinukleotid fosfatna reduktaza, NAD(P)+-rubredoksinska oksidoreduktaza, NAD(P)H-rubredoksinska oksidoreduktaza) je enzim sa sistematskim imenom rubredoksin:NAD(P)+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Rubredoksin—NAD(P)+ reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.18.1.4 | ||||||||
| CAS broj | 80237-97-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 redukovani rubredoksin + NAD(P)+ + H+ 2 oksidovani rubredoksin + NAD(P)H
Za rad enzima iz Pirococcus furiosus je neophodan FAD.
Reference uredi
- ↑ Petitdemange, H., Blusson, H. and Gay, R. (1981). „Detection of NAD(P)H-rubredoxin oxidoreductases in Clostridia”. Anal. Biochem. 116: 564-570. PMID 6274224.
- ↑ Ma, K. and Adams, M.W.W. (1999). „A hyperactive NAD(P)H:rubredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus”. J. Bacteriol. 181: 5530-5533. PMID 10464233.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.