Riboza 1,5-bisfosfat fosfokinaza
Riboza 1,5-bisfosfat fosfokinaza (EC 2.7.4.23, riboza 1,5-bisfosfokinaza, PhnN) je enzim sa sistematskim imenom ATP:riboza-1,5-bisfosfat fosfotransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Riboza 1,5-bisfosfat fosfokinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.4.23 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim, prisutan u NAD supresivnim mutantima bakterije Escherichia coli, sintetiše 5-fosfo-alfa-D-riboza 1-difosfat (PRPP), bez učešća enzima EC 2.7.6.1, riboza-fosfat difosfokinaza.
Reference uredi
- ↑ Hove-Jensen, B., Rosenkrantz, T.J., Haldimann, A. and Wanner, B.L. (2003). „Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity (phosphoribosyl diphosphate forming): dual role in phosphonate degradation and NAD biosynthesis pathways”. J. Bacteriol. 185: 2793-2801. PMID 12700258.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.