Crveni hlorofil katabolit reduktaza
(Preusmjereno sa stranice RCC reduktaza)
Crveni hlorofil katabolit reduktaza (EC 1.3.1.80, RCCR, RCC reduktaza, red Chl katabolitna reduktaza) je enzim sa sistematskim imenom primarni fluorscentni hlorofilni katabolit:NADP+ oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Crveni hlorofil katabolit reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.80 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- primarni fluorscent hlorofil katabolit + NADP+ red hlorofil katabolit + NADPH + H+
Degradacija hlorofila je karakteristični simptom starenja lišća i sazrevanja voća. Za reakciju koju katalizuje ovaj enzim neophodan je redukovani feredoksin, koji se formira bilo putem NADPH u putu pentoznog-fosfata ili dejstvom fotosistema I. Ova reakcija se odvija bez otpuštanja supstrata iz EC 1.14.12.20, feoforbid a oksigenaze.
Reference
uredi- ↑ Rodoni, S., Mühlecker, W., Anderl, M., Kräutler, B., Moser, D., Thomas, H., Matile, P. and Hörtensteiner, S. (1997). „Chlorophyll breakdown in senescent chloroplasts. Cleavage of pheophorbide a in two enzymic steps”. Plant Physiol. 115: 669-676. PMID 12223835.
- ↑ Wüthrich, K.L., Bovet, L., Hunziker, P.E., Donnison, I.S. and Hörtensteiner, S. (2000). „Molecular cloning, functional expression and characterisation of RCC reductase involved in chlorophyll catabolism”. Plant J. 21: 189-198. PMID 10743659.
- ↑ Pružinská, A., Anders, I., Aubry, S., Schenk, N., Tapernoux-Lüthi, E., Müller, T., Kräutler, B. and Hörtensteiner, S. (2007). „In vivo participation of red chlorophyll catabolite reductase in chlorophyll breakdown”. Plant Cell 19: 369-387. PMID 17237353.
- ↑ Hörtensteiner, S. (2006). „Chlorophyll degradation during senescence”. Annu. Rev. Plant Biol. 57: 55-77. PMID 16669755.
- ↑ Rodoni, S., Vicentini, F., Schellenberg, M., Matile, P. and Hörtensteiner, S. (1997). „Partial purification and characterization of red chlorophyll catabolite reductase, a stroma protein involved in chlorophyll breakdown”. Plant Physiol. 115: 677-682. PMID 12223836.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.