Prekorin-6Y C5,15-metiltransferaza (dekarboksilacija)
Prekorin-6Y C5,15-metiltransferaza (dekarboksilacija) (EC 2.1.1.132, prekorin-6 metiltransferaza, prekorin-6Y metilaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:1-prekorin-6Y C5,15-metiltransferaza (C-12-dekarboksilacija).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prekorin-6Y C5,15-metiltransferaza (dekarboksilacija) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.132 | ||||||||
| CAS broj | 162995-22-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 S-adenozil-L-metionin + prekorin-6Y 2 S-adenozil-L-homocistein + prekorin-8X + CO2
Enzim iz Pseudomonas denitrificans deluje kao S-adenozil-L-metionin-zavisna metiltransferaza i dekarboksilaza.
Reference uredi
- ↑ Blanche, F., Famechon, A., Thibaut, D., Debussche, L., Cameron, B., Crouzet, J. (1992). „Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6Y to precorrin-8X is catalyzed by the cobL gene product”. J. Bacteriol. 174: 1050-1052. PMID 1732195.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.