Prekorin-3B C17-metiltransferaza
Prekorin-3B C17-metiltransferaza (EC 2.1.1.131, prekorin-3 metiltransferaza, CobJ) je enzim sa sistematskim imenom S-adenozil-L-metionin:prekorin-3B C17-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prekorin-3B C17-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.131 | ||||||||
| CAS broj | 152787-64-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + prekorin-3B S-adenozil-L-homocistein + prekorin-4
Ovaj enzim učestvuje u aerobnom kobalaminskom biositetičkom putu.
Reference uredi
- ↑ Scott, A.I., Roessner, C.A., Stolowich, N.J., Spencer, J.B., Min, C. and Ozaki, S.I. (1993). „Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group”. FEBS Lett. 331: 105-108. PMID 8405386.
- ↑ Debussche, L., Thibaut, D., Cameron, B., Crouzet, J. and Blanche, F. (1993). „Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans”. J. Bacteriol. 175: 7430-7440. PMID 8226690.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.