Piritiaminska deaminaza
Piritiaminska deaminaza (EC 3.5.4.20) je enzim sa sistematskim imenom 1-(4-amino-2-metilpirimid-5-ilmetil)-3-(beta-hidroksietil)-2-metilpiridinium-bromid aminohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Piritiaminska deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.4.20 | ||||||||
| CAS broj | 37289-23-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 1-(4-amino-2-metilpirimid-5-ilmetil)-3-(beta-hidroksietil)-2-metilpiridinijum bromid + H2O 1-(4-hidroksi-2-metilpirimid-5-ilmetil)-3-(beta-hidroksietil)-2-metilpiridinijum bromid + NH3
Reference uredi
- ↑ Sinha, A.K. and Chatterjee, G.C. (1968). „Metabolism of pyrithiamine by the pyrithiamine-requiring mutant of Staphylococcus aureus'”. Biochem. J. 107: 165-169. PMID 5641872.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.