Peptidilna dipeptidaza Dcp
Peptidilna dipeptidaza Dcp (EC 3.4.15.5, dipeptidilna karboksipeptidaza (Dcp), dipeptidilna karboksipeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Peptidilna dipeptidaza Dcp | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.15.5 | ||||||||
| CAS broj | 395642-28-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza neblokiranog, C-terminalnog dipeptida sa oligopeptida, sa širokom specifičnošću. Ne dolazi do hidrolize veza kod kojih P1' jeste Pro, ili su P1 i P1' Gly
Ovaj enzim je izolovan iz Escherichia coli i Salmonella typhimurium.
Reference uredi
- ↑ Yaron, A. (1976). „Dipeptidyl carboxypeptidase from Escherichia coli”. Methods Enzymol. 45: 599-610. PMID 13271.
- ↑ Henrich, B., Becker, S., Schroeder, U. and Plapp, R. (1993). „dcp gene of Escherichia coli: cloning, sequencing, transcript mapping, and characterization of the gene product”. J. Bacteriol. 175: 7290-7300. PMID 8226676.
- ↑ Conlin, C.A. and Miller, C.G. (1995). „Oligopeptidase A and peptidyl-dipeptidase of Escherichia and Salmonella”. Methods Enzymol. 248: 567-579. PMID 7674945.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.