Pektatna trisaharid-lijaza
Pektatna trisaharid-lijaza (EC 4.2.2.22, eksopektat-lijaza, pektat lijaza A, PelA) je enzim sa sistematskim imenom (1->4)-alfa-D-galakturonan redukujuči-kraj-trisaharid-lijaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pektatna trisaharid-lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.2.22 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Eliminativno odvajanje nezasićenog trigalakturonata kao glavnog produkta sa redukujućeg kraja poligalakturonske kiseline/pektata
Ovaj enzim prvenstveno uklanja trisaharid sa redukujućeg kraja.
Reference uredi
- ↑ Kluskens, L.D., van Alebeek, G.J., Voragen, A.G., de Vos, W.M. and van der Oost, J. (2003). „Molecular and biochemical characterization of the thermoactive family 1 pectate lyase from the hyperthermophilic bacterium Thermotoga maritima”. Biochem. J. 370: 651-659. PMID 12443532.
- ↑ Tamaru, Y. and Doi, R.H. (2001). „Pectate lyase A, an enzymatic subunit of the Clostridium cellulovorans cellulosome”. Proc. Natl. Acad. Sci. USA 98: 4125-4129. PMID 11259664.
- ↑ Berensmeier, S., Singh, S.A., Meens, J. and Buchholz, K. (2004). „Cloning of the pelA gene from Bacillus licheniformis 14A and biochemical characterization of recombinant, thermostable, high-alkaline pectate lyase”. Appl. Microbiol. Biotechnol. 64: 560-567. PMID 14673544.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.