Palmitoil-KoA hidrolaza
Palmitoil-KoA hidrolaza (EC 3.1.2.2, dugolančana masna-acil-KoA hidrolaza, palmitoil koenzim A hidrolaza, palmitoilna tioesteraza, palmitoil koenzim A hidrolaza, palmitoil-KoA deacilaza, palmitil tioesteraza, palmitil-KoA deacilaza, masna acil tioesteraza I, palmitil tioesteraza I) je enzim sa sistematskim imenom palmitoil-KoA hidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Palmitoil-KoA hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.2.2 | ||||||||
| CAS broj | 9025-87-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- palmitoil-KoA + H2O KoA + palmitat
Ovaj enzijm takođe hidrolizuje KoA tioestre drugih dugolančanih masnih kiselina.
Reference uredi
- ↑ Barnes, E.M., Jr. and Wakil, S.J. (1968). „Studies on the mechanism of fatty acid synthesis. XIX. Preparation and general properties of palmityl thioesterase”. J. Biol. Chem. 243: 2955-2962. PMID 4871199.
- ↑ Berge, R.K. and Farstad, M. (1981). „Long-chain fatty acyl-CoA hydrolase from rat liver mitochondria”. Methods Enzymol. 71: 234-242. PMID 6116156.
- ↑ Miyazawa, S., Furuta, S. and Hashimoto, T. (1981). „Induction of a novel long-chain acyl-CoA hydrolase in rat liver by administration of peroxisome proliferators”. Eur. J. Biochem. 117: 425-430. PMID 6115749.
- ↑ Srere, P.A., Seubert, W. and Lynen, F. (1959). „Palmityl coenzyme A deacylase”. Biochim. Biophys. Acta 33: 313-319. PMID 13670899.
- ↑ Yabusaki, K.K. and Ballou, C.E. (1981). „Long-chain fatty acyl-CoA thioesterases from Mycobacterium smegmatis”. Methods Enzymol. 71: 242-246.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.