Palmitoil(protein) hidrolaza
Palmitoil(protein) hidrolaza (EC 3.1.2.22, palmitoil-protein tioesteraza, palmitoil-(protein) hidrolaza) je enzim sa sistematskim imenom palmitoil(protein) hidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Palmitoil(protein) hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.2.22 | ||||||||
| CAS broj | 150605-49-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim je specifičan za dugolančane tioestre masnih kiselina.
Reference uredi
- ↑ Camp, L.A., Hofmann, S.L. (1995). „Assay and isolation of palmitoyl-protein thioesterase from bovine brain using palmitoylated H-Ras as substrate”. Methods Enzymol. 250: 336-347. PMID 7651163.
- ↑ Schriner, J.E., Yi, W., Hofmann, S.L. (1996). „cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis”. Genomics, 34: 317-322. PMID 8786130.
- ↑ Verkruyse, L.A., Hofmann, S.L. (1996). „Lysosomal targeting of palmitoyl-protein thioesterase”. J. Biol. Chem. 271: 15831-15836. PMID 8663305.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.