Putrescin karbamoiltransferaza
(Preusmjereno sa stranice PTCase)
Putrescin karbamoiltransferaza (EC 2.1.3.6, PTCaza, putrescinska sintaza, putrescinska transkarbamilaza) je enzim sa sistematskim imenom karbamoil-fosfat:putrescin karbamoiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Putrescin karbamoiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.3.6 | ||||||||
| CAS broj | 9076-55-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- karbamoil fosfat + putrescin fosfat + N-karbamoilputrescin
Ovaj biljni enzim takođe katalizuje reakcije EC 2.1.3.3, ornitin karbamoiltransferaze, EC 2.7.2.2, karbamatne kinaze i EC 3.5.3.12, agmatinske deiminaze. On deluje kao putrescinska sintaza, koja konvertuje agmatin [(4-aminobutil)guanidin] i ornitin u putrescin i citrulin, respektivno.
Reference uredi
- ↑ Roon, R.J. and Barker, H.A. (1972). „Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase”. J. Bacteriol. 109: 44-50. PMID 4621632.
- ↑ Srivenugopal, K.S. and Adiga, P.R. (1981). „Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase)”. J. Biol. Chem. 256: 9532-9541. PMID 6895223.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.