Cinamoil-KoA reduktaza
(Preusmjereno sa stranice P-hidroksicinamoil koenzim A reduktaza)
Cinamoil-KoA reduktaza (EC 1.2.1.44, feruloil-KoA reduktaza, cinamoil-koenzim A reduktaza, ferulil-KoA reduktaza, feruloil koenzim A reduktaza, p-hidroksicinamoil koenzim A reduktaza, cinamoil-KoA:NADPH reduktaza) je enzim sa sistematskim imenom cinamaldehid:NADP+ oksidoreduktaza (KoA-cinamoilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Cinamoil-KoA reduktaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.2.1.44 | ||||||||
CAS broj | 59929-39-4 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- cinamaldehid + KoA + NADP+ cinamoil-KoA + NADPH + H+
Ovaj enzim takođe deluje na brojene supstituisane cinamoilne estere koenzima A.
Reference uredi
- ↑ Gross, G.G. and Kreiten, W. (1975). „Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia”. FEBS Lett. 54: 259-262. PMID 236926.
- ↑ Sarni, F., Grand, C. and Baudet, A.M. (1984). „Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana)”. Eur. J. Biochem. 139: 259-265. PMID 6365550.
- ↑ Wengenmayer, H., Ebel, J. and Grisebach, H. (1976). „Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax)”. Eur. J. Biochem. 65: 529-536. PMID 7454.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.