Nuatigenin 3b-glukoziltransferaza
Nuatigenin 3b-glukoziltransferaza (EC 2.4.1.192, uridin difosfoglukoza-nuatigenin glukoziltransferaza) je enzim sa sistematskim imenom UDP-glukoza:(20S,22S,25S)-22,25-epoksifurost-5-en-3beta,26-diol 3-O-beta-D-glukoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Nuatigenin 3b-glukoziltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.1.192 | ||||||||
CAS broj | 108891-57-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- UDP-glukoza + (20S,22S,25S)-22,25-epoksifurost-5-en-3beta,26-diol UDP + (20S,22S,25S)-22,25-epoksifurost-5-en-3beta,26-diol 3-O-beta-D-glukozid
Poznato je da i drugi sapogenini mogu da deluju kao glukozilni akceptori. Poznato je da ovaj enzim učestvuje u biosintezi biljnih saponina.
Reference
uredi- ↑ Kalinowska, M. and Wojciechowski, Z.A. (1986). „Enzymatic-synthesis of nuatigenin 3-β-D-glucoside in oat (Avena sativa) leaves”. Phytochemistry 25: 2525-2529.
- ↑ Kalinowska, M. and Wojciechowski, Z.A. (1987). „Subcellular-localization of UDPG-nuatigenin glucosyltransferase in oat leaves”. Phytochemistry 26: 353-357.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.