Nikotinamid-nukleotid adenililtransferaza
Nikotinamid-nukleotid adenililtransferaza (EC 2.7.7.1, NAD+ pirofosforilaza, adenozin trifosfat-nikotinamid mononukleotid transadenilaza, ATP:NMN adenililtransferaza, difosfopiridin nukleotid pirofosforilaza, nikotinamid adenin dinukleotid pirofosforilaza, nikotinamid mononukleotid adenililtransferaza, NMN adenililtransferaza) je enzim sa sistematskim imenom ATP:nikotinamid-nukleotid adenililtransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Nikotinamid-nukleotid adenililtransferaza | |||||||||
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| Heksamer nikotinamid-nukleotid adenililtransferaze (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.7.1 | ||||||||
| CAS broj | 9032-70-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Nikotinatni nukleotid takođe može da deluje kao akceptor.
Reference
uredi- ↑ Atkinson, M.R., Jackson, J.F. and Morton, R.K. (1961). „Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei. The effects of nicotinamide mononucleotide concentration and pH on dinucleotide synthesis”. Biochem. J. 80: 318-323. PMID 13684981.
- ↑ Dahmen, W., Webb, B. and Preiss, J. (1967). „The deamido-diphosphopyridine nucleotide and diphosphopyridine nucleotide pyrophosphorylases of Escherichia coli and yeast”. Arch. Biochem. Biophys. 120: 440-450. PMID 4291828.
- ↑ Kornberg, A. and Pricer, W.E. (1951). „Enzymatic cleavage of diphosphopyridine nucleotide with radioactive pyrophosphate”. J. Biol. Chem. 191: 535-541. PMID 14861199.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.