Nezasićena ramnogalakturonilna hidrolaza
Nezasićena ramnogalakturonilna hidrolaza (EC 3.2.1.172, YteR, YesR) je enzim sa sistematskim imenom 2-O-(4-dezoksi-beta-L-treo-heks-4-enopiranuronozil)-alfa-L-ramnopiranoza hidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Nezasićena ramnogalakturonilna hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.172 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-O-(4-dezoksi-beta-L-treo-heks-4-enopiranuronozil)-alfa-L-ramnopiranoza + H2O 5-dehidro-4-dezoksi-D-glukuronat + L-ramnopiranoza
Ovaj enzim učestvuje u degradaciji ramnogalakturonana I kod Bacillus subtilis vrste 168.
Reference uredi
- ↑ Itoh, T., Ochiai, A., Mikami, B., Hashimoto, W. and Murata, K. (2006). „A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide”. J. Mol. Biol. 360: 573-585. PMID 16781735.
- ↑ Zhang, R., Minh, T., Lezondra, L., Korolev, S., Moy, S.F., Collart, F. and Joachimiak, A. (2005). „1.6 Å crystal structure of YteR protein from Bacillus subtilis, a predicted lyase”. Proteins 60: 561-565. PMID 15906318.
- ↑ Itoh, T., Ochiai, A., Mikami, B., Hashimoto, W. and Murata, K. (2006). „Structure of unsaturated rhamnogalacturonyl hydrolase complexed with substrate”. Biochem. Biophys. Res. Commun. 347: 1021-1029. PMID 16870154.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.