NADPH dehidrogenaza
NADPH dehidrogenaza (EC 1.6.99.1, NADPH2 dijaforaza, NADPH dijaforaza, OYE, dijaforaza, dihidronikotinamid adenin dinukleotid fosfat dehidrogenaza, NADPH-dehidrogenaza, NADPH-dijaforaza, NADPH2-dehidrogenaza, redukovani nikotinamid adenin dinukleotid fosfat dehidrogenaza, TPNH dehidrogenaza, TPNH-dijaforaza, trifosfopiridinska dijaforaza, trifosfopiridin nukleotidna dijaforaza, NADPH2 dehidrogenaza, NADPH:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom NADPH:akceptor oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADPH dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.99.1 | ||||||||
| CAS broj | 9001-68-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- NADPH + H+ + akceptor NADP+ + redukovani akceptor
Ovaj enzim je flavoprotein (FMN kod kvasaca, FAD kod biljki).
Reference
uredi- ↑ Åkesson, Å., Ehrenberg, A. and Theorell, H. (1963). „Old yellow enzyme”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 477-494.
- ↑ Avron, M. and Jagendorf, A.T. (1957). „Some further investigations on chloroplast TPNH diaphorase”. Arch. Biochem. Biophys. 72: 17-24. PMID 13471057.
- ↑ Jagendorf, A.T. (1963). „Chloroplast TPNH diaphorase”. Methods Enzymol. 6: 430-434.
- ↑ Theorell, H. (1935). „Das gelbe Oxydationsferment”. Biochem. Z. 278: 263-290.
- ↑ Theorell, H. and Åkesson, Å. (1956). „Molecular weight and FMN content of crystalline "old yellow enzyme"”. Arch. Biochem. Biophys. 65: 439-448. PMID 13373435.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.