NADH peroksidaza
NADH peroksidaza (EC 1.11.1.1, DPNH peroksidaza, NAD peroksidaza, difosfopiridin nukleotidna peroksidaza, NADH-peroksidaza, nikotinamid adenin dinukleotidna peroksidaza, NADH2 peroksidaza) je enzim sa sistematskim imenom NADH:vodonik-peroksid oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADH peroksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.11.1.1 | ||||||||
| CAS broj | 9032-24-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- NADH + H+ + H2O2 NAD+ + 2H2O
Ovaj enzim je flavoprotein (FAD). Fericijanid i hinoni mogu da zamene H2O2.
Reference
uredi- ↑ Domagk, G.F. and Horecker, B.L. (1965). „Fructose and erythrose metabolism in Alcaligenes faecalis”. Arch. Biochem. Biophys. 109: 342-349.
- ↑ Mizushima, S. and Kitahara, K. (1962). „Purification and properties of DPNH peroxidase in Lactobacillus casei”. J. Gen. Appl. Microbiol. 8: 56-62.
- ↑ Walker, G.A. and Kilgour, G.L. (1965). „Pyridine nucleotide oxidizing enzymes of Lactobacillus casei. II. Oxidase and peroxidase”. Arch. Biochem. Biophys. 131: 534-539. PMID 4285876.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.