NADH:ubihinon reduktaza (neelektrogena)
NADH:ubihinon reduktaza (neelektrogena) (EC 1.6.5.9, ubihinonska reduktaza, koenzim Q reduktaza, dihidronikotinamid adenin dinukleotid-koenzim Q reduktaza, DPNH-koenzim Q reduktaza, DPNH-ubihinon reduktaza, NADH-koenzim Q oksidoreduktaza, NADH-koenzim Q reduktaza, NADH-CoQ oksidoreduktaza, NADH-CoQ reduktaza, NADH-ubihinonska reduktaza, NADH-ubihinonska oksidoreduktaza, redukovani nikotinamid adenin dinukleotid-koenzim Q reduktaza, NADH-Q6 oksidoreduktaza, kompleks transfera elektrona I, NADH2 dehidrogenaza (ubihinon)) je enzim sa sistematskim imenom NADH:ubihinon oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADH:ubihinon reduktaza (neelektrogena) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.5.9 | ||||||||
| CAS broj | 9028-04-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim je flavoprotein (FAD). On se javlja u mitohondrijama kvasaca i biljki, i u aerobnim bakterijama.
Reference
uredi- ↑ Moller, I.M, and Palmer, J.M. (1982). „Direct evidence for the presence of a rotenone-resistant NADH dehydrogenase on the inner surface of plant mitochondria”. Physiologia Plantarum 54: 267-274.
- ↑ de Vries, S. and Grivell, L.A. (1988). „Purification and characterization of a rotenone-insensitive NADH:Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae”. Eur. J. Biochem. 176: 377-384. PMID 3138118.
- ↑ Kerscher, S.J., Okun, J.G. and Brandt, U. (1999). „A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica”. J. Cell Sci. 112 ( Pt 14): 2347-2354. PMID 10381390.
- ↑ Rasmusson, A.G., Soole, K.L. and Elthon, T.E. (2004). „Alternative NAD(P)H dehydrogenases of plant mitochondria”. Annu. Rev. Plant Biol. 55: 23-39. PMID 15725055.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.