Metilaspartatna mutaza
Metilaspartatna mutaza (EC 5.4.99.1, glutamatna mutaza, glutaminaka mutaza, glutaminska izomeraza, glutaminsko kiselinska mutaza, glutamisko kiselinska izomeraza, metilaspartinsko kiselinska mutaza, beta-metilaspartat-glutamatna mutaza, glutamatna izomeraza) je enzim sa sistematskim imenom L-treo-3-metilaspartat karboksi-aminometilmutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilaspartatna mutaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.1 | ||||||||
| CAS broj | 9032-97-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-treo-3-metilaspartat L-glutamat
Za dejstvo ovog enzima je neophodan kobamidni koenzim.
Reference uredi
- ↑ Barker, H.A., Rooze, V., Suzuki, F. and Iodice, A.A. (1964). „The glutamate mutase system. Assays and properties”. J. Biol. Chem. 239: 3260-3266. PMID 14245371.
- ↑ Weissbach, H., Toohey, J. and Barker, H.A. (1959). „Isolation and properties of B12 coenzymes containing benzimidazole or dimethylbenzimidazole”. Proc. Natl. Acad. Sci. USA 45: 521-528. PMID 16590408.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.