Membranska Pro-X karboksipeptidaza
Membranska Pro-X karboksipeptidaza (EC 3.4.17.16, karboksipeptidaza P, mikrozomalna karboksipeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Membranska Pro-X karboksipeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.16 | ||||||||
| CAS broj | 9075-64-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje C-terminalnih ostataka osim prolina, sa preferencijom za razlaganje prolil veze
Ovaj enzim je jedna od renalnih eksopeptidaza.
Reference
uredi- ↑ Dehm, P. and Nordwig, A. (1970). „The cleavage of prolyl peptides by kidney peptidases. Isolation of a microsomal carboxypeptidase from swine kidney”. Eur. J. Biochem. 17: 372-377. PMID 5500406.
- ↑ Booth, A.G., Hubbard, L.M.L. and Kenny, A.J. (1979). „Proteins of the kidney microvillar membrane. Immunoelectrophoretic analysis of the membrane hydrolase: identification and resolution of the detergent- and proteinase-solubilized forms”. Biochem. J. 179: 397-405. PMID 486090.
- ↑ Hedeager-Sorensen, S. and Kenny, A.J. (1985). „Proteins of the kidney microvillar membrane. Purification and properties of carboxypeptidase P from pig kidneys”. Biochem. J. 229: 251-257. PMID 4038259.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.