Manitol dehidrogenaza (citohrom)
Manitol dehidrogenaza (citohrom) (EC 1.1.2.2, poliolna dehidrogenaza) je enzim sa sistematskim imenom D-manitol:citohrom-c 2-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Manitol dehidrogenaza (citohrom) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.2.2 | ||||||||
| CAS broj | 37250-78-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-manitol + fericitohrom c D-fruktoza + ferocitohrom c + 2 H+
Ovaj enzim iz bakterije Gluconobacter oksidans deluje na poliole sa D-likso konfiguracijom, kao što su D-manitol i D-sorbitol, sa preferencijom za manitol.
Reference
uredi- ↑ Arcus, A.C. and Edson, N.L. (1956). „Polyol dehydrogenases. 2. The polyol dehydrogenases of Acetobacter suboxydans and Candida utilis”. Biochem. J. 64: 385-394. PMID 13373782.
- ↑ Cho, N.C., Kim, K. and Jhon, D.Y. (1990). „Purification and characterization of polyol dehydrogenase from Gluconobacter melanogenus”. Han'guk Saenghwa Hakhaochi 23: 172-178.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.