Maltoza O-acetiltransferaza
Maltoza O-acetiltransferaza (EC 2.3.1.79, maltozna transacetilaza, maltozna O-acetiltransferaza, MAT) je enzim sa sistematskim imenom acetil-KoA:maltoza O-acetiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Maltoza O-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.79 | ||||||||
| CAS broj | 81295-47-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acetil-KoA + maltoza KoA + 6-O-acetil-alfa-D-glukopiranozil-(1->4)-D-glukoza
Ovaj enzim nije identičan sa EC 2.3.1.18, galaktozid O-acetiltransferazom. Acetil grupa se dodaje samo u C6 poziciji glukoze i u C6 poziciji neredukujućeg glukoznog ostatka maltoze.
Reference
uredi- ↑ Freundlieb, S. and Boos, W. (1982). „Maltose transacetylase of Escherichia coli: a preliminary report”. Ann. Microbiol. (Paris) 133A: 181-189. PMID 7041741.
- ↑ Brand, B. and Boos, W. (1991). „Maltose transacetylase of Escherichia coli. Mapping and cloning of its structural, gene, mac, and characterization of the enzyme as a dimer of identical polypeptides with a molecular weight of 20,000”. J. Biol. Chem. 266: 14113-14118. PMID 1856235.
- ↑ Lo Leggio, L., Dal Degan, F., Poulsen, P., Andersen, S.M. and Larsen, S. (2003). „The structure and specificity of Escherichia coli maltose acetyltransferase give new insight into the LacA family of acyltransferases”. Biochemistry 42: 5225-5235. PMID 12731863.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.