Maleilacetoacetatna izomeraza
Maleilacetoacetatna izomeraza (EC 5.2.1.2, maleilacetoacetinska izomeraza, maleilacetonska izomeraza, maleilaceton cis-trans-izomeraza) je enzim sa sistematskim imenom 4-maleilacetoacetat cis-trans-izomeraza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Maleilacetoacetatna izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.2.1.2 | ||||||||
| CAS broj | 9023-75-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-maleilacetoacetat 4-fumarilacetoacetat
Ovaj enzim takođe deluje na maleilpiruvat.
Reference uredi
- ↑ Edwards, S.W. and Knox, W.E. (1956). „Homogentisate metabolism: the isomerization of maleylacetoacetate by an enzyme which requires glutathione”. J. Biol. Chem. 220: 79-91. PMID 13319328.
- ↑ Lack, L. (1961). „Enzymic cis-trans isomerization of maleylpyruvic acid”. J. Biol. Chem. 236: 2835-2840. PMID 14461395.
- ↑ Seltzer, S. (1973). „Purification and properties of maleylacetone cis-trans isomerase from Vibrio 01”. J. Biol. Chem. 248: 215-222. PMID 4692831.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.