Malat dehidrogenaza (NADP+)
Malat dehidrogenaza (NADP+) (EC 1.1.1.82, NADP+-malatni enzim, NADP+-malatna dehidrogenaza, malatna dehidrogenaza (nikotinamid adenin dinukleotid fosfat), malat NADP+ dehidrogenaza, NADP+ malatna dehidrogenaza, NADP+-vezana malatna dehidrogenaza) je enzim sa sistematskim imenom (S)-malat:NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Malat dehidrogenaza (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.1.1.82 | ||||||||
| CAS broj | 37250-19-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (S)-malat + NADP+ oksaloacetat + NADPH + H+
Malatna dehidrogenaza se aktivira svetlošću.
Reference
uredi- ↑ Connelly, J.L., Danner, D.J. and Bowden, J.A. (1968). „Branched chain α-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver α-ketoisocaproic:α-keto-β-methylvaleric acid dehydrogenase”. J. Biol. Chem. 243: 1198-1203. PMID 5689906.
- ↑ Johnson, H.S. (1971). „NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis”. Biochem. Biophys. Res. Commun. 43: 703-709. PMID 4397919.
- ↑ Johnson, H.S. and Hatch, M.D. (1970). „Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis”. Biochem. J. 119: 273-280. PMID 4395182.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.