Lizin-tRNK ligaza (EC 6.1.1.6, lizil-tRNK sintetaza, lizil-transfer ribonukleat sintetaza, lizil-transfer RNK sintetaza, L-lizin-transfer RNK ligaza, lizin-tRNK sintetaza, lizinska translaza) je enzim sa sistematskim imenom L-lizin:tRNKLis ligaza (formira AMP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + L-lizin + tRNKLys AMP + difosfat + L-lizil-tRNKLys
- ↑ Allen, E.H., Glassman, E. and Schweet, R.S. (1960). „Incorporation of amino acids into ribonucleic acid. I. The role of activating enzymes”. J. Biol. Chem. 235: 1061-1067. PMID 13792726.
- ↑ Chiumecka, V., von Tigerstrom, M., D'Obrenan, P. and Smith, C.J. (1969). „Purification and properties of lysyl transfer ribonucleic acid synthetase from bakers' yeast”. J. Biol. Chem. 244: 5481-5488. PMID 4310598.
- ↑ Lagerkvist, U., Rymo, L., Lindqvist, O. and Andersson, E. (1972). „Some properties of crystals of lysine transfer ribonucleic acid ligase from yeast”. J. Biol. Chem. 247: 3897-3899. PMID 4555953.
- ↑ Stern, R. and Mehler, A.H. (1965). „Lysyl-sRNA synthetase from Escherichia coli”. Biochem. Z. 342: 400-409. PMID 4284804.
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