Linaloolna dehidrataza
Linaloolna dehidrataza (EC 4.2.1.127, linaloolna hidrolijaza (formira mircen)) je enzim sa sistematskim imenom (3S)-linalool hidrolijaza (formira mircen).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Linaloolna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.127 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
U odsustvu kiseonika ova bifunkcionalna linalool dehidrataza-izomeraza može da in vitro katalizuje dve reakcije, hidraciju mircena do (3S)-linaloola i izomerizaciju (3S)-linaloola do geraniola.
Reference uredi
- ↑ Brodkorb, D., Gottschall, M., Marmulla, R., Lüddeke, F. and Harder, J. (2010). „Linalool dehydratase-isomerase, a bifunctional enzyme in the anaerobic degradation of monoterpenes”. J. Biol. Chem. 285: 30436-30442. PMID 20663876.
- ↑ Lüddeke, F. and Harder, J. (2011). „Enantiospecific (S)-(+)-linalool formation from β-myrcene by linalool dehydratase-isomerase”. Z. Naturforsch. C 66: 409-412. PMID 21950166.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.