Leucilna endopeptidaza
Leucilna endopeptidaza (EC 3.4.21.57, biljna Leu-proteinaza, leucin-specifična serinska proteinaza, leucinska endopeptidaza, serinska proteinaza španaća (specifična za leucin), španaćna leucin-specifična serinska proteinaza, Leu-proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Leucilna endopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.57 | ||||||||
| CAS broj | 136396-22-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza proteina. Preferentno razlaganje veze Leu- u supstratima koji su mali molekuli
Ovaj enzim je izolovan iz lišća španaća (Spinacia oleracea)
Reference uredi
- ↑ Aducci, P., Ascenzi, P., Pierini, M. and Ballio, A. (1986). „Purification and characterization of Leu-proteinase, the leucine specific serine proteinase from spinach (Spinacia oleracea L.) leaves”. Plant Physiol. 81: 812-816. PMID 16664908.
- ↑ Aducci, P., Ascenzi, P. and Ballio, A. (1986). „Esterolytic properties of leucine-proteinase, the leucine-specific serine proteinase from spinach (Spinacia oleracea L.)”. Plant Physiol. 82: 591-593. PMID 16665073.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.