Karoten epsilon-monooksigenaza
(Preusmjereno sa stranice LUT1)
Karoten epsilon-monooksigenaza (EC 1.14.99.45, CYP97C1, LUT1) je enzim sa sistematskim imenom alfa-karoten:kiseonik oksidoreduktaza (3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Karoten epsilon-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.99.45 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- alfa-karoten + O2 + AH2 alfa-kriptoksantin + A + H2O
Ovaj enzim je hem-tiolatni protein. On takođe deluje na zeinoksantin i formira lutein.
Reference uredi
- ↑ Pogson, B., McDonald, K.A., Truong, M., Britton, G. and DellaPenna, D. (1996). „Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants”. Plant Cell 8: 1627-1639. PMID 8837513.
- ↑ Tian, L., Musetti, V., Kim, J., Magallanes-Lundback, M. and DellaPenna, D. (2004). „The Arabidopsis LUT1 locus encodes a member of the cytochrome P450 family that is required for carotenoid ε-ring hydroxylation activity”. Proc. Natl. Acad. Sci. USA 101: 402-407. PMID 14709673.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.