Krotonoil-(acil-nosilac-protein) hidrataza
Krotonoil-(acil-nosilac-protein) hidrataza (EC 4.2.1.58, (3R)-3-hidroksibutanoil-(acil-nosilac-protein) hidrolijaza, beta-hidroksibutiril acil nosilac protein (ACP) dehidraza, beta-hidroksibutiril acil nosilac protein dehidraza, enoil acil nosilac protein hidraza, krotonil acil nosilac protein hidrataza, 3-hidroksibutiril acil nosilac protein dehidrataza, beta-hidroksibutiril acil nosilac, proteinska dehidraza, (3R)-3-hidroksibutanoil-(acil-nosilac-protein) hidrolijaza (formira but-2-enoil-(acil-nosilac protein))) je enzim sa sistematskim imenom (3R)-3-hidroksibutanoil-(acil-nosilac protein) hidrolijaza (formira but-2-enoil-(acil-nosilac protein)).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Krotonoil-(acil-nosilac-protein) hidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.58 | ||||||||
| CAS broj | 9030-78-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (3R)-3-hidroksibutanoil-[acil-nosilac protein] but-2-enoil-[acil-nosilac protein] + H2O
Ovaj enzim je specifičan kratkolančane 3-hidroksiacil-[acil-nosilac protein] derivate (C4 do C8).
Reference uredi
- ↑ Majerus, P.W., Alberts, A.W. and Vagelos, P.R. (1965). „Acyl carrier protein. 3. An enoyl hydrase specific for acyl carrier protein thioesters”. J. Biol. Chem. 240: 618-621. PMID 14275113.
- ↑ Mizugaki, M., Weeks, G., Toomey, R.E. and Wakil, S.J. (1968). „Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of β-hydroxybutyryl acyl carrier protein dehydrase”. J. Biol. Chem. 243: 3661-3670. PMID 5658542.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.