Karotenoid-9',10'-razlaganje dioksigenaza
Karotenoid-9',10'-razlaganje dioksigenaza (EC 1.13.11.71, BCO2 (gen)) je enzim sa sistematskim imenom sve-trans-beta-karoten:O2 oksidoreduktaza (9',10'-razlaganje).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Karotenoid-9',10'-razlaganje dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.71 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- sve-trans-beta-karoten + O2 sve-trans-10'-apo-beta-karotenal + beta-jonon
Ovaj enzim sadrži Fe2+. On katalizuje asimetrično oksidativno razlaganje karotenoida.
Reference uredi
- ↑ Kiefer, C., Hessel, S., Lampert, J.M., Vogt, K., Lederer, M.O., Breithaupt, D.E. and von Lintig, J. (2001). „Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A”. J. Biol. Chem. 276: 14110-14116. PMID 11278918.
- ↑ Lindqvist, A., He, Y.G. and Andersson, S. (2005). „Cell type-specific expression of β-carotene 9′,10′-monooxygenase in human tissues”. J. Histochem. Cytochem. 53: 1403-1412. PMID 15983114.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.