Izoprenska sintaza
Izoprenska sintaza (EC 4.2.3.27, ISPC, ISPS) je enzim sa sistematskim imenom dimetilalil-difosfat difosfat-lijaza (formira izopren).[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Izoprenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.27 | ||||||||
| CAS broj | 139172-14-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Za dejstvo ovog enzima su neophodni joni Mg2+ i Mn2+.
Reference uredi
- ↑ Silver, G.M. and Fall, R. (1991). „Enzymatic synthesis of isoprene from dimethylallyl diphosphate in aspen leaf extracts”. Plant Physiol. 97: 1588-1591. PMID 16668590.
- ↑ Silver, G.M. and Fall, R. (1995). „Characterization of aspen isoprene synthase, an enzyme responsible for leaf isoprene emission to the atmosphere”. J. Biol. Chem. 270: 13010-13016. PMID 7768893.
- ↑ Wildermuth, M.C. and Fall, R. (1996). „Light-dependent isoprene emission (characterization of a thylakoid-bound isoprene synthase in Salix discolor chloroplasts)”. Plant Physiol. 112: 171-182. PMID 12226383.
- ↑ Schnitzler, J.P., Arenz, R., Steinbrecher, R. and Lehming, A. (1996). „Characterization of an isoprene synthase from leaves of Quercus petraea”. Bot. Acta 109: 216-221.
- ↑ Miller, B., Oschinski, C. and Zimmer, W. (2001). „First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli”. Planta 213: 483-487. PMID 11506373.
- ↑ Sivy, T.L., Shirk, M.C. and Fall, R. (2002). „Isoprene synthase activity parallels fluctuations of isoprene release during growth of Bacillus subtilis”. Biochem. Biophys. Res. Commun. 294: 71-75. PMID 12054742.
- ↑ Sasaki, K., Ohara, K. and Yazaki, K. (2005). „Gene expression and characterization of isoprene synthase from Populus alba”. FEBS Lett. 579: 2514-2518. PMID 15848197.
- ↑ Schnitzler, J.-P., Zimmer, I., Bachl, A., Arend, M., Fromm, J. and Fischbach, R.J. (2005). „Biochemical properties of isoprene synthase in poplar (Populus x canescens)”. Planta 222: 777-786. PMID 16052321.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.