Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4
(Preusmjereno sa stranice IPNV Vp4 proteaza)
Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 (EC 3.4.21.115, proteaza virusa infektine pankreasne nekroze, IPNV Vp4 proteaza, IPNV Vp4 peptidaza, NS proteaza, NS-asocirana proteaza, Vp4 proteaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 | |||||||||
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Identifikatori | |||||||||
EC broj | 3.4.21.115 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Presecanje (Ser/Thr)-Xaa-Ala-(Ser/Ala)-Gly motiva u poliproteinu NH2-pVP2-VP4-VP3-COOH infektinog pankreasnog nekroznog virusa na pVP2-VP4 i VP4-VP3 spojevima
Infektivni pankreasni nekrozni virus (IPNV) je birnavirus koji uzrokuje akutnu, zaraznu bolest kod mladih pastrmki.
Reference uredi
- ↑ Manning, D.S. and Leong, J.C. (1990). „Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus”. Virology 179: 16-25. PMID 2219718.
- ↑ Petit, S., Lejal, N., Huet, J.C. and Delmas, B. (2000). „Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus”. J. Virol. 74: 2057-2066. PMID 10666235.
- ↑ Dobos, P. (1995). „The molecular biology of infectious pancreatic necrosis virus (IPNV)”. Annu. Rev. Fish Dis. 5: 25-54.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.