Histidinol-fosfat transaminaza
(Preusmjereno sa stranice IAP transaminaza)
Histidinol-fosfat transaminaza (EC 2.6.1.9, imidazolilacetolfosfatna transaminaza, glutaminska-imidazoleacetol fosfatna transaminaza, histidinol fosfatna aminotransferaza, imidazoleacetol fosfatna transaminaza, L-histidinol fosfatna aminotransferaza, histidin:imidazoleacetol fosfatna transaminaza, IAP transaminaza, imidazolilacetolfosfatna aminotransferaza) je enzim sa sistematskim imenom L-histidinol-fosfat:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Histidinol-fosfat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Histidinol-fosfat transaminaza homodimer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.6.1.9 | ||||||||
| CAS broj | 9032-98-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- L-histidinol fosfat + 2-oksoglutarat 3-(imidazol-4-il)-2-oksopropil fosfat + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Ames, B.N. and Horecker, B.L. (1956). „The biosynthesis of histidine: imidazoleacetol phosphate transaminase”. J. Biol. Chem. 220: 113-128. PMID 13319331.
- ↑ Martin, R.G. and Goldberger, R.F. (1963). „Imidazolylacetolphosphate:L-glutamate aminotransferase. Purification and properties”. J. Biol. Chem. 242: 1168-1174. PMID 5337155.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.