Hlorofilid-a oksigenaza
(Preusmjereno sa stranice Hlorofil-b sintaza)
Hlorofilid-a oksigenaza (EC 1.14.13.122, hlorofilid a oksigenaza, hlorofil-b sintaza, CAO) je enzim sa sistematskim imenom hlorofilid-a:kiseonik 7-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hlorofilid-a oksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.122 | ||||||||
| CAS broj | 216503-73-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) hlorofilid a + O2 + NADPH + H+ 7-hidroksihlorofilid a +H2O + NADP+
- (2) 7-hidroksihlorofilid a + O2 + NADPH + H+ hlorofilid b + 2H2O + NADP+
Hlorofil b je neophodan za formiranje stabilnog kompleksa ubiranja svetlosti kod hloroplastnih zelenih algi, cijanobakterija i biljki.
Reference uredi
- ↑ Espineda, C.E., Linford, A.S., Devine, D. and Brusslan, J.A. (1999). „The AtCAO gene, encoding chlorophyll a oxygenase, is required for chlorophyll b synthesis in Arabidopsis thaliana”. Proc. Natl. Acad. Sci. USA 96: 10507-10511. PMID 10468639.
- ↑ Oster, U., Tanaka, R., Tanaka, A. and Rüdiger, W. (2000). „Cloning and functional expression of the gene encoding the key enzyme for chlorophyll b biosynthesis (CAO) from Arabidopsis thaliana”. Plant J. 21: 305-310. PMID 10758481.
- ↑ Eggink, L.L., LoBrutto, R., Brune, D.C., Brusslan, J., Yamasato, A., Tanaka, A. and Hoober, J.K. (2004). „Synthesis of chlorophyll b: localization of chlorophyllide a oxygenase and discovery of a stable radical in the catalytic subunit”. BMC Plant Biol. 4: 5-5. PMID 15086960.
- ↑ Porra, R.J., Schafer, W., Cmiel, E., Katheder, I. and Scheer, H. (1994). „The derivation of the formyl-group oxygen of chlorophyll b in higher plants from molecular oxygen. Achievement of high enrichment of the 7-formyl-group oxygen from 18O2 in greening maize leaves”. Eur. J. Biochem. 219: 671-679. PMID 8307032.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.