Hloridazon-katehol dioksigenaza
Hloridazon-katehol dioksigenaza (EC 1.13.11.36, hloridazon-kateholna dioksigenaza) je enzim sa sistematskim imenom 5-amino-4-hloro-2-(2,3-dihidroksifenil)-3(2H)-piridazinonska 1,2-oksidoreduktaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Hloridazon-katehol dioksigenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.13.11.36 | ||||||||
CAS broj | 82869-32-7 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 5-amino-4-hloro-2-(2,3-dihidroksifenil)-3(2H)-piridazinon + O2 5-amino-4-hloro-2-(2-hidroksimukonoil)-3(2H)-piridazinon
Ovaj enzim sadrži gvožđe.
Reference
uredi- ↑ Müller, R, Haug, S., Eberspächer, J. and Lingens, F. (1977). „Catechol-2,3-Dioxygenase aus Pyrazon-abbauenden Bakterien”. Hoppe-Seyler's Z. Physiol. Chem. 358: 797-805. PMID 19349.
- ↑ Müller, R., Schmitt, S. and Lingens, F. (1982). „A novel non-heme iron-containing dioxygenase. Chloridazon-catechol dioxygenase from Phenylobacterium immobilis DSM 1986”. Eur. J. Biochem. 125: 579-584. PMID 6811270.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.