Hidroksilamin reduktaza (NADH)
Hidroksilamin reduktaza (NADH) (EC 1.7.1.10, hidroksilaminska reduktaza, amonijumska dehidrogenaza, NADH-hidroksilaminska reduktaza, N-hidroksi aminska reduktaza, hidroksilaminska reduktaza (NADH2), NADH2:hidroksilaminska oksidoreduktaza) je enzim sa sistematskim imenom amonijum:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hidroksilamin reduktaza (NADH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.7.1.10 | ||||||||
| CAS broj | 2605070 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- NH3 + NAD+ + H2O hidroksilamin + NADH + H+
Ovaj enzim takođe deluje na pojedine hidroksamate.
Reference
uredi- ↑ Bernheim, M.L.C. (1969). „The hydroxylamine reductase of mitochondria”. Arch. Biochem. Biophys. 134: 408-413. PMID 4311180.
- ↑ Bernheim, M.L.C. and Hochstein, P. (1968). „Reduction of hydroxylamine by rat liver mitochondria”. Arch. Biochem. Biophys. 124: 436-442. PMID 4298499.
- ↑ Wang, R. and Nicholas, D.J.D. (1986). „Some properties of nitrite and hydroxylamine reductases from Derxia gummosa”. Phytochemistry 25: 2463-2469.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.