Ribonukleaza H telećeg timusa
(Preusmjereno sa stranice Hibridaza (ribonukleaza H))
Ribonukleaza H telećeg timusa (EC 3.1.26.4, endoribonukleaza H (teleća grudna žlezda), RNaza H, RNK*DNK hibridna ribonukleotidohidrolaza, hibridna ribonukleaza, hibridaza, hibridaza (ribonukleaza H), ribonukleaza H, hibridna nukleaza, ribonukleaza H teleće grudne žlezde) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ribonukleaza H telećeg timusa | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.1.26.4 | ||||||||
| CAS broj | 9050-76-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Endonukleolitičko razlaganje do 5'-fosfomonoestara
Ovaj enzim deluje na RNK-DNK hibride.
Reference
uredi- ↑ Haberkern, R.C. and Cantoni, G.L. (1973). „Studies on a calf thymus ribonuclease specific for ribonucleic acid-deoxyribonucleic acid hybrids”. Biochemistry 12: 2389-2395. PMID 4709937.
- ↑ Stavrianopoulos, J.G. and Chargaff, E. (1973). „Purification and properties of ribonuclease H of calf thymus”. Proc. Natl. Acad. Sci. USA 70: 1959-1963. PMID 4516197.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.