Riboflavin sintaza
(Preusmjereno sa stranice Heavy riboflavin synthase)
Riboflavin sintaza (EC 2.5.1.9, sintaza teškog riboflavina, sinaza lakog riboflavina, riboflavinska sintetaza, riboflavinska sintaza, riboflavinska sintetaza) je enzim sa sistematskim imenom 6,7-dimetil-8-(1-D-ribitil)lumazin:6,7-dimetil-8-(1-D-ribitil)lumazin 2,3-butandiiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Riboflavin sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.5.1.9 | ||||||||
| CAS broj | 9075-82-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 2 6,7-dimetil-8-(1-D-ribitil)lumazin riboflavin + 4-(1-D-ribitilamino)-5-amino-2,6-dihidroksipirimidin
Ovaj enzim je flavoprotein (riboflavin).
Reference uredi
- ↑ Plaut, G.W.E. (1963). „Studies on the nature of the enzymic conversion of 6,7-dimethyl-8-ribityllumazine to riboflavin”. J. Biol. Chem. 238: 2225-2243. PMID 13944007.
- ↑ Plaut, G.W.E. and Harvey, R.A. (1971). „Riboflavin synthetase”. Methods Enzymol. 18B: 527-538.
- ↑ Wacker, H., Harvey, R.A., Winestock, C.H. and Plaut, G.W.E. (1964). „4-(1′-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine, the second product of the riboflavin synthetase reaction”. J. Biol. Chem. 239: 3493-3497. PMID 14245407.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.