D-glicero-alfa-D-mano-heptoza-7-fosfat kinaza
(Preusmjereno sa stranice Hdda (gen))
D-glicero-alfa-D-mano-heptoza-7-fosfat kinaza (EC 2.7.1.168, D-alfa-D-heptoza-7-fosfat kinaza, hdda (gen)) je enzim sa sistematskim imenom ATP:D-glicero-alfa-D-mano-heptoza 7-fosfat 1-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
D-glicero-alfa-D-mano-heptoza-7-fosfat kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.168 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim učeststvuje u biosintezi GDP-D-glicero-alfa-D-mano-heptoze, što je neophodno za formiranje S-sloja glikoproteina kod Gram-pozitivnih bakterija.
Reference uredi
- ↑ Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. (2001). „Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose”. J. Biol. Chem. 276: 20935-20944. PMID 11279237.
- ↑ Valvano, M.A., Messner, P. and Kosma, P. (2002). „Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides”. Microbiology 148: 1979-1989. PMID 12101286.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.