Guanilat kinaza
Guanilat kinaza (EC 2.7.4.8, dezoksiguanilatna kinaza, 5'-GMP kinaza, GMP kinaza, guanozin monofosfatna kinaza, ATP:GMP fosfotransferaza) je enzim sa sistematskim imenom ATP:(d)GMP fosfotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Guanilat kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.7.4.8 | ||||||||
| CAS broj | 9026-59-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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dGMP takođe deluje kao akceptor, dok dATP može da bude donor.
Reference
uredi- ↑ Buccino, R.J., Jr. and Roth, J.S. (1969). „Partial purification and properties of ATP:GMP phosphotransferase from rat liver”. Arch. Biochem. Biophys. 132: 49-61. PMID 4307347.
- ↑ Hiraga, S. and Sugino, Y. (1966). „Nucleoside monophosphokinases of Escherichia coli infected and uninfected with an RNA phage”. Biochim. Biophys. Acta 114: 416-418. PMID 5329274.
- ↑ Griffith, T.J. and Helleiner, C.W. (1965). „The partial purification of deoxynucleoside monophosphate kinases from L cells”. Biochim. Biophys. Acta 108: 114-124. PMID 5862227.
- ↑ Oeschger, M.P. and Bessman, M.J. (1966). „Purification and properties of guanylate kinase from Escherichia coli”. J. Biol. Chem. 241: 5452-5460. PMID 5333666.
- ↑ Shimono, H. and Sugino, Y. (1971). „Metabolism of deoxyribonucleotides. Purification and properties of deoxyguanosine monophosphokinase of calf thymus”. Eur. J. Biochem. 19: 256-263. PMID 5552394.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.