Glutamat dehidrogenaza

Glutamat dehidrogenaza
Identifikatori
EC broj	1.4.1.2
CAS broj	9001-46-1
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Glutamat dehidrogenaza (EC 1.4.1.2, glutaminska dehidrogenaza, glutamatna dehidrogenaza (NAD⁺), glutamatna oksidoreduktaza, glutamatna kiselina dehidrogenaza, L-glutamatna dehidrogenaza, NAD⁺-zavisna glutamatna dehidrogenaza, NAD⁺-glutamatna dehidrogenaza, NAD⁺-vezana glutamatna dehidrogenaza, NAD⁺-vezana glutamatna dehidrogenaza, NAD⁺-specifična glutamatna dehidrogenaza, NAD⁺-specifična glutamatna dehidrogenaza, NAD⁺:glutamatna oksidoreduktaza, NADH-vezana glutamatna dehidrogenaza) je enzim sa sistematskim imenom L-glutamat:NAD⁺ oksidoreduktaza (deaminacija).^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-glutamat +H₂O + NAD⁺

\rightleftharpoons

2-oksoglutarat + NH₃ + NADH + H⁺

Reference uredi

↑ Frieden, C. (1963). „L-Glutamate dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 3-24.
↑ Nisman, B. (1954). „The Stickland reaction”. Bacteriol. Rev. 18: 16-42. PMID 13140081.
↑ Pahlich, E. and Joy, K.W. (1971). „Glutamate dehydrogenase from pea roots: purification and properties of the enzyme”. Can. J. Biochem. 49: 127-138. PMID 4324282.
↑ Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. (1975). „Glutamate dehydrogenases”. u: Boyer, P.D.. The Enzymes. 11 (3rd izd.). New York: Academic Press. str. 293-367.

Literatura uredi

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Spoljašnje veze uredi

MeSH Glutamate+dehydrogenase

[1] Frieden, C. (1963). „L-Glutamate dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 3-24.

[2] Nisman, B. (1954). „The Stickland reaction”. Bacteriol. Rev. 18: 16-42. PMID 13140081.

[3] Pahlich, E. and Joy, K.W. (1971). „Glutamate dehydrogenase from pea roots: purification and properties of the enzyme”. Can. J. Biochem. 49: 127-138. PMID 4324282.

[4] Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. (1975). „Glutamate dehydrogenases”. u: Boyer, P.D.. The Enzymes. 11 (3rd izd.). New York: Academic Press. str. 293-367.

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