Glutamat—prefenat aminotransferaza
Glutamat—prefenat aminotransferaza (EC 2.6.1.79, prefenatna transaminaza, PAT, L-glutamat:prefenat aminotransferaza) je enzim sa sistematskim imenom L-arogenat:2-oksoglutarat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glutamat—prefenat aminotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.79 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim je piridoksal-fosfatni protein. Aspartat takođe može da deluje kao amino donor, mada sporije.
Reference uredi
- ↑ Bonner, C.A. and Jensen, R.A. (1985). „Novel features of prephenate aminotransferase from cell cultures of Nicotiana silvestris”. Arch. Biochem. Biophys. 238: 237-246. PMID 3985619.
- ↑ Siehl, D.L., Connelly, J.A. and Conn, E.E. (1986). „Tyrosine biosynthesis in Sorghum bicolor: characteristics of prephenate aminotransferase”. Z. Naturforsch. 41: 79-86. PMID 2939644.
- ↑ Bonner, C. and Jensen, R. (1987). „Prephenate aminotransferase”. Methods Enzymol. 142: 479-487. PMID 3298985.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.