Glukoza 1-dehidrogenaza
Glukoza 1-dehidrogenaza (EC 1.1.1.47, D-glukozna dehidrogenaza (NAD(P)+), heksoza fosfat dehidrogenaza) je enzim sa sistematskim imenom beta-D-glukoza:NAD(P)+ 1-oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukoza 1-dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Tetramer glukoza dehidrogenaze (Caenorhabditis elegans) | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.1.1.47 | ||||||||
| CAS broj | 9028-53-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- beta-D-glukoza + NAD(P)+ D-glukono-1,5-lakton + NAD(P)H + H+
Takođe oksiduje D-ksilozu.
Reference uredi
- ↑ Banauch, D., Brummer, W., Ebeling, W., Metz, H., Rindfrey, H., Lang, H., Leybold, K. and Rick, W. (1975). „A glucose dehydrogenase for the determination of glucose concentrations in body fluids”. Z. Klin. Chem. Klin. Biochem. 13: 101-107. PMID 810982.
- ↑ Brink, N.G. (1953). „Beef liver glucose dehydrogenase. 1. Purification and properties”. Acta Chem. Scand. 7: 1081-1089.
- ↑ Pauly, H.E. and Pfleiderer, G. (1976). „D-Glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure”. Hoppe-Seyler's Z. Physiol. Chem. 356: 1613-1623.
- ↑ Strecker, H.J. and Korkes, S. (1952). „Glucose dehydrogenase”. J. Biol. Chem. 196: 769-784. PMID 12981017.
- ↑ Thompson, R.E. and Carper, W.R. (1970). „Glucose dehydrogenase from pig liver. I. Isolation and purification”. Biochim. Biophys. Acta 198: 397-406. PMID 4392298.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.