Glicerofosfoholinska fosfodiestaraza
Glicerofosfoholinska fosfodiestaraza (EC 3.1.4.2, glicerofosfinikoholinska diesteraza, glicerilfosforilholindiesteraza, sn-glicero-3-fosforilholin diesteraza, glicerolfosforilholinska fosfodiesteraza, glicerofosfohidrolaza) je enzim sa sistematskim imenom sn-glicero-3-fosfoholin glicerofosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glicerofosfoholinska fosfodiestaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.4.2 | ||||||||
| CAS broj | 9025-85-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- sn-glicero-3-fosfoholin + H2O holin + sn-glicerol 3-fosfat
Ovaj enzim takođe deluje na sn-glicero-3-fosfoetanolamin.
Reference uredi
- ↑ Dawson, R.M.C. (1956). „Liver glycerylphosphorylcholine diesterase”. Biochem. J. 62: 689-693. PMID 13315235.
- ↑ Hayaishi, O. and Kornberg, A. (1954). „Metabolism of phospholipides by bacterial enzymes”. J. Biol. Chem. 206: 647-663. PMID 13143024.
- ↑ Webster, G.R., Marples, E.A. and Thompson, R.H.S. (1957). „Glycerylphosphorylcholine diesterase activity in nervous tissue”. Biochem. J. 65: 374-377. PMID 13403918.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.