GMP sintaza (hidrolizacija glutamina)
(Preusmjereno sa stranice GMP sintetaza (glutaminska hidroliza))
GMP sintaza (hidrolizacija glutamina) (EC 6.3.5.2, GMP sintetaza (glutaminska hidroliza), guanilatna sintetaza (glutaminska hidroliza), guanozin monofosfatna sintetaza (glutaminska hidroliza), ksantozin 5'-fosfatna amidotransferaza, guanozin 5'-monofosfatna sintetaza) je enzim sa sistematskim imenom ksantozin-5'-fosfat:L-glutamin amido-ligaza (formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| GMP sintaza (hidrolizacija glutamina) | |||||||||
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| Identifikatori | |||||||||
| EC broj | 6.3.5.2 | ||||||||
| CAS broj | 37318-71-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Reference
uredi- ↑ Abrams, R. and Bentley, M. (1959). „Biosynthesis of nucleic acid purines. III. Guanosine 5′-phosphate formation from xanthosine 5′-phosphate and L-glutamine”. Arch. Biochem. Biophys. 79: 91-110.
- ↑ Lagerkvist, U. (1958). „Biosynthesis of guanosine 5′-phosphate. II. Amination of xanthosine 5′-phosphate by purified enzyme from pigeon liver”. J. Biol. Chem. 233: 143-149. PMID 13563458.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.