Celuloza sintaza (formira GDP)
(Preusmjereno sa stranice GDP-glukoza:(1-4)-beta-D-glukan 4-beta-D-glukoziltransferaza)
Celuloza sintaza (formira GDP) (EC 2.4.1.29, celulozna sintaza (formira guanozin difosfat), celulozna sintetaza, guanozin difosfoglukoza-1,4-beta-glukan glukoziltransferaza, guanozin difosfoglukoza-celulozna glukoziltransferaza, GDP-glukoza:1,4-beta-D-glukan 4-beta-D-glukoziltransferaza) je enzim sa sistematskim imenom GDP-glukoza:(1->4)-beta-D-glukan 4-beta-D-glukoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Celuloza sintaza (formira GDP) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.29 | ||||||||
| CAS broj | 9027-18-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- GDP-glukoza + [(1->4)-beta-D-glukozil]n GDP + [(1->4)-beta-D-glukozil]n+1
Ovaj enzim učestvuje u sintezi celuloze. Slični enzim EC 2.4.1.12, celulozna sintaza (formira UDP)] koristi UDP-glukozu.
Reference uredi
- ↑ Chambers, J.C. and Elbein, A.D. (1970). „Biosynthesis of glucans in mung bean seedlings. Formation of β-(1,4)-glucans from GDP-glucose and β-(1,3)-glucans from UDP-glucose”. Arch. Biochem. Biophys. 138: 620-631. PMID 4317490.
- ↑ Flowers, H.M., Batra, K.K., Kemp, J. and Hassid, W.Z. (1969). „Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus' and Lupinus albus”. J. Biol. Chem. 244: 4969-4674. PMID 5824571.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.