Guanidinobutiraza
(Preusmjereno sa stranice G-Base)
Guanidinobutiraza (EC 3.5.3.7, gama-guanidobutiraza, 4-guanidinobutiratna amidinobutiraza, gama-guanidinobutiratna amidinohidrolaza, G-Baza, GBH, guanidinobutiratna urejahidrolaza) je enzim sa sistematskim imenom 4-guanidinobutanoat amidinohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Guanidinobutiraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.3.7 | ||||||||
| CAS broj | 9013-69-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-guanidinobutanoat + H2O 4-aminobutanoat + ureja
Za dejstvo ovog enzima je neopohdan jon Mn2+.
Reference uredi
- ↑ Mora, J., Tarrab, R., Martuscelli, J. and Soberón, G. (1965). „Characteristics of arginases from ureotelic and non-ureotelic animals”. Biochem. J. 96: 588-594. PMID 5862400.
- ↑ Thoai, N.V., Thome-Beau, F. and Olomucki, A. (1966). „[Induction and specificity of enzymes of the new catabolic arginine pathway]”. Biochim. Biophys. Acta 115: 73-80. PMID 5936244.
- ↑ Yorifuji, T., Kato, M., Kobayashi, T., Ozaki, S. and Ueno, S. (1980). „4-Guanidinobutyrate amidinohydrolase from Pseudomonas sp ATCC 14676: purification to homogeneity and properties”. Agric. Biol. Chem. 44: 1127-1134.
- ↑ Yorifuji, T., Kobayashi, T., Tabuchi, A., Shiritani, Y. and Yonaha, K. (1983). „Distribution of amidinohydrolases among Pseudomonas and comparative studies of some purified enzymes by one-dimensional peptide mapping”. Agric. Biol. Chem. 47: 2825-2830.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.