Fosforilaza kinaza
Fosforilaza kinaza (EC 2.7.11.19, defosfofosforilazna kinaza, fosforilazna kinaza (fosforilacija), glikogen fosforilazna kinaza, fosforilazna b kinaza) je enzim sa sistematskim imenom ATP:fosforilaza-b fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosforilaza kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.7.11.19 | ||||||||
| CAS broj | 9001-88-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 4 ATP + 2 fosforilaza b 4 ADP + fosforilaza a
Reference uredi
- ↑ Krebs, E.G. and Fischer, E.H. (1956). „The phosphorylase b to a converting enzyme of rabbit skeletal muscle”. Biochim. Biophys. Acta 20: 150-157. PMID 13315361.
- ↑ Krebs, E.G., Kent, A.B. and Fischer, E.H. (1958). „The muscle phosphorylase b kinase reaction”. J. Biol. Chem. 231: 73-83. PMID 13538949.
- ↑ Rall, T.W., Wosilait, W.D. and Sutherland, E.W. (1956). „The interconversion of phosphorylase a and phosphorylase b from dog heart muscle”. Biochim. Biophys. Acta 20: 69-76. PMID 13315351.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.