Fosfatidilserinska dekarboksilaza
Fosfatidilserinska dekarboksilaza (EC 4.1.1.65, PS dekarboksilaza, fosfatidil-L-serinska karboksilijaza) je enzim sa sistematskim imenom fosfatidil-L-serin karboksilijaza (formira fosfatidiletanolamin).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Fosfatidilserinska dekarboksilaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.1.1.65 | ||||||||
CAS broj | 9054-78-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- fosfatidil-L-serin fosfatidiletanolamin + CO2
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Kanfer, J. and Kennedy, E.P. (1964). „Metabolism and function of bacterial lipids. II. Biosynthesis of phospholipids in Escherichia coli”. J. Biol. Chem. 239: 1720-1726. PMID 14213340.
- ↑ Satre, M. and Kennedy, E.P. (1978). „Identification of bound pyruvate essential for the activity of phosphatidylserine decarboxylase of Escherichia coli”. J. Biol. Chem. 253: 479-483. PMID 338609.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.