Fosfat acetiltransferaza
Fosfat acetiltransferaza (EC 2.3.1.8, fosfotransacetilaza, fosfoacilaza, PTA) je enzim sa sistematskim imenom acetil-KoA:fosfat acetiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosfat acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Fosfat acetiltransferaza homodimer, Methanosarcina thermophila | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.3.1.8 | ||||||||
| CAS broj | 9029-91-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- acetil-KoA + fosfat KoA + acetil fosfat
Ovaj enzim takođe deluje na druge kratkolančane acil-KoA.
Reference uredi
- ↑ Bergmeyer, H.U., Holz, G., Klotzsch, H. and Lang, G. (1963). „Phosphotransacetylase aus Clostridium kluyveri. Züchtung des Bacteriums, Isolierung, Krystallisation und Eigenschaften des Enzyms”. Biochem. Z. 338: 114-121. PMID 14087284.
- ↑ Stadtman, E.R. (1952). „The purification and properties of phosphotransacetylase”. J. Biol. Chem. 196: 527-534. PMID 12980995.
- ↑ Stadtman, E.R. (1955). „Phosphotransacetylase from Clostridium kluyveri”. Methods Enzymol. 1: 596-599.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.